Poster Presentation International Pasteurellaceae Conference 2014

Actinobacillus pleuropneumoniae in biofilms in swine farms in Mexico (#48)

Abraham Loera Muro 1 , Alma Lilián Guerrero Barrera 1 , Mario Jacques 2 , Josée Labrie 2 , Yannick D.N. Tremblay 2 , Flor Y. Ramí­rez Castillo 1 , Ricardo Oropeza Navarro 3 , Francisco Javier Avelar González 1
  1. Universidad Autónoma de Aguascalientes, Aguascalientes, AG, Mexico
  2. Université de Montréal, Saint-Hyacinthe, QC, Canada
  3. Instituto de Biotecnología, UNAM, Cuernavaca, MR, Mexico
Actinobacillus pleuropneumoniae is the etiological agent of porcine contagious pleuropneumonia, which causes important worldwide economic losses in the swine industry. Fifteen serotypes of A. pleuropneumoniae have been described based on capsular antigens and two biotypes have been described based on nicotinamide adenosine dinocleotide (NAD) requeriments. A. pleuropneumoniae has traditionally been considered an obligate pathogen of pigs. However the presence of A. pleuropneumoniae in the environment has yet to be thoroughly investigated. Here was detected A. pleuropneumoniae, found in biofilms isolated from drinking water and directly in the drinkers of swine farms. Samples of drinking water were taken directly from the watering places in the swine farm. A. pleuropneumoniae detection was performed by PCR analysis using primers again apxIV toxin gene. A total of 14 farms and 84 drinking water samples were obtained. Detection of A. pleuropneumoniae in drinking water was achieved in 5 farms in a first general screening; and from 3 of them were able to obtain 20 positives samples. Also, in these samples were detected for 16S rDNA Stenotrophomonas maltophilia, Acinetobacter schindleri and Escherichia coli. All samples had the ability to form biofilms in vitro and A. pleuropneumoniae biofilm formation was observed in vivo by FISH assay with others bacteria. In conclusion, our data suggest that this A. pleuropneumoniae has the ability to survive in aquatic environments using biofilms to survive outside its host, and could be surviving in association with other bacteria in a multi-species biofilm.